Program

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at the LNLS entrance hall

Welcoming remarks

IYCr2014 and the summit meetings

From Laue to present Latin America

The future in Latin America: Sirius Project

Structural Biology and multidisciplinarity at the LNBio

Coffe Break

Novel insights into bacterial signaling: the ‘one sequence ‐ multiple structures’ perspective

S-SAD phasing of monoclinic histidine kinase from Brucella abortus at low resolution using true redundancy and multiple crystal data collection

The Physiological Function of the Xanthomonas Type IV Secretion System

Lunch at the campus

Crystallographic and protein engineering studies of Triosephosphate isomerase

How different techniques such as Spectroscopy, proteomics, and in silico approaches, are associated to X-ray crystallography to obtain structural information in a complex system, the Phycobilisome

Decoding cellular information with tandem-repeat galectins

Coffee Break

Tautomerase Superfamily – good things come in small packages

Can structures lead to advanced therapeutics?

Presentation of odd numbered posters + Social Gathering

Some structural insights into mycobacterial signalling mechanisms

X-rays and sound pulses: acoustic methods in crystallography and drug discovery

Structural and biophysical studies of human Methionine Adenosyltransferases

Structure-function relationships of anaerobic metalloenzymes

Coffee Break

UNESCO and the International Year of Cristallography

Participants: Pedro Alzari, Alexei Soares, Adriana Rojas and Juan Fontecilla-Camps

Lunch at the campus

Progress in the field of Chemistry of Natural Products in the Faculty of Natural Sciences at Nacional University of Asunción

Different ways to bind cofactors: allosteric ATP inhibition and NAD(P) binding selectivity

Structural characterization of the enzymes in the naphthalene degradation pathway: filling the gaps

Coffee Break

Unraveling Problems in Protein Misfolding Diseases using Structural Biology and Bioimaging

Unraveling the mechanism of assembly of the CuA center in cytochrome oxidases

Structure and dynamics of protein-DNA interactions in transcription initiation complexes of Escherichia coli

The molecular basis of the relaxation and activation of tarantula striated muscle thick filament is revealed by the disclosure of the myosin interacting-heads motif structure

Presentation of even numbered posters + Social Gathering

Insights into c-di-GMP-mediated transcriptional mechanisms involved in biofilm formation of Pseudomonas aeruginosa

Using X-rays to describe electronic fluxes in REDOX enzymes

Bacterial mimicry of eukaryotic innate immunity

Intrinsic disorder and unstructural biology

Coffee Break

NMR in structural biology: Beyond the structures

A Cryo-Electron Microscopy Facility for Single Particle Analysis at the National Center for Energy and Materials Research

Centro de Biología Estuctural del Mercosur (CeBEM)

Latin American Crystallography Association (LACA)

Closing Remarks

Lunch at the campus

22nd September 2014

08:00 - 08:45
Registration

at the LNLS entrance hall

08:45 - 09:00
Kleber Franchini

Welcoming remarks

Introduction - Chair: Glaucius Oliva
09:00 - 09:30
Marvin Hackert (IUCr President)

IYCr2014 and the summit meetings

Historical Perspective on Protein Crystallography in Latin America - Chair: Richard Garratt (BRA)
09:30 - 10:00
Glaucius Oliva (IFSC/USP)

From Laue to present Latin America

10:00 - 10:30
Antonio José Roque (LNLS)

The future in Latin America: Sirius Project

10:30 - 11:00
Kleber Franchini (LNBio)

Structural Biology and multidisciplinarity at the LNBio

11:00 - 11:30

Coffe Break

Biological Crystallography 1 - Chair: Adela Rodríguez-Romero (MEX)
11:30 - 12:00
Alejandro Buschiazzo (URU)

Novel insights into bacterial signaling: the ‘one sequence ‐ multiple structures’ perspective

12:00 - 12:30
Sebastian Klinke (ARG)

S-SAD phasing of monoclinic histidine kinase from Brucella abortus at low resolution using true redundancy and multiple crystal data collection

12:30 - 13:00
Chuck Farah (BRA)

The Physiological Function of the Xanthomonas Type IV Secretion System

13:00 - 14:30

Lunch at the campus

Biological Crystallography 2 - Chair: Marcos Fontes (BRA)
14:30 - 15:00
Luis Brieba (MEX)

Crystallographic and protein engineering studies of Triosephosphate isomerase

15:00 - 15:30
Marta Bunster (CHI)

How different techniques such as Spectroscopy, proteomics, and in silico approaches, are associated to X-ray crystallography to obtain structural information in a complex system, the Phycobilisome

15:30 - 16:00
Maria Cristina Nonato (BRA)

Decoding cellular information with tandem-repeat galectins

16:00 - 16:30

Coffee Break

Chair: Glaucius Oliva (BRA)
16:30 - 17:00
Marvin Hackert (IUCr President)

Tautomerase Superfamily – good things come in small packages

17:00 - 18:00
Keynote Lecture: Ada Yonath

Can structures lead to advanced therapeutics?

18:00 - 20:30
Poster Session 1

Presentation of odd numbered posters + Social Gathering

23rd September 2014
A View From Abroad: Latin Americans Working Overseas - Chair: Samar Hasnain (IUCr)
09:00 - 09:30
Pedro Alzari (FRA)

Some structural insights into mycobacterial signalling mechanisms

09:30 - 10:00
Alexei Soares (USA)

X-rays and sound pulses: acoustic methods in crystallography and drug discovery

10:00 - 10:30
Adriana Rojas (ESP)

Structural and biophysical studies of human Methionine Adenosyltransferases

10:30 - 11:00
Juan Fontecilla-Camps (FRA)

Structure-function relationships of anaerobic metalloenzymes

11:00 - 11:30

Coffee Break

11:30 - 12:00
Lidia Brito (UNESCO)

UNESCO and the International Year of Cristallography

12:00 - 13:20
Round-table mediated by Samar Hasnain (IUCr)

Participants: Pedro Alzari, Alexei Soares, Adriana Rojas and Juan Fontecilla-Camps

13:20 - 14:00

Lunch at the campus

Biological Crystallography 3 - Chair: Sergio Pantano (URU)
14:30 - 15:00
Miguel Angel Martínez Cabrera (PAR)

Progress in the field of Chemistry of Natural Products in the Faculty of Natural Sciences at Nacional University of Asunción

15:00 - 15:30
Ricardo Cabrera (CHI)

Different ways to bind cofactors: allosteric ATP inhibition and NAD(P) binding selectivity

15:30 - 16:00
Ronaldo Nagem (BRA)

Structural characterization of the enzymes in the naphthalene degradation pathway: filling the gaps

16:00 - 16:30

Coffee Break

Complementary Techniques 1 - Chair: Roberto Salinas (BRA)
16:30 - 17:00
Jerson Lima da Silva (BRA)

Unraveling Problems in Protein Misfolding Diseases using Structural Biology and Bioimaging

17:00 - 17:30
Alejandro Vila (ARG)

Unraveling the mechanism of assembly of the CuA center in cytochrome oxidases

17:30 - 18:00
Daniel Guerra (PER)

Structure and dynamics of protein-DNA interactions in transcription initiation complexes of Escherichia coli

18:00 - 18:30
Raul Padrón (VEN)

The molecular basis of the relaxation and activation of tarantula striated muscle thick filament is revealed by the disclosure of the myosin interacting-heads motif structure

18:30 - 21:00
Poster Session 2

Presentation of even numbered posters + Social Gathering

24th September 2014
Biological Crystallography 4 - Chair: Rafael V. Guido (BRA)
09:00 - 09:30
Marcos Navarro (BRA)

Insights into c-di-GMP-mediated transcriptional mechanisms involved in biofilm formation of Pseudomonas aeruginosa

09:30 - 10:00
Enrique Rudino-Pinera (MEX)

Using X-rays to describe electronic fluxes in REDOX enzymes

10:00 - 10:30
Andrea Dessen (BRA)

Bacterial mimicry of eukaryotic innate immunity

10:30 - 11:00
Gonzalo Prat Gay (ARG)

Intrinsic disorder and unstructural biology

11:00 - 11:30

Coffee Break

Complementary Techniques 2 - Chair: Marcelo Costabel (ARG)
11:30 - 12:00
Ana Carolina Zeri (BRA)

NMR in structural biology: Beyond the structures

12:00 - 12:30
Rodrigo Portugal (BRA)

A Cryo-Electron Microscopy Facility for Single Particle Analysis at the National Center for Energy and Materials Research

12:30 - 12:45
Alejandro Buschiazzo (URU)

Centro de Biología Estuctural del Mercosur (CeBEM)

12:45 - 13:00
Iris Torriani

Latin American Crystallography Association (LACA)

13:00 - 13:10
Samar Hasnain

Closing Remarks

13:10 - 14:30

Lunch at the campus