{"id":4972,"date":"2025-06-12T14:49:28","date_gmt":"2025-06-12T17:49:28","guid":{"rendered":"https:\/\/pages.cnpem.br\/rau\/?p=4972"},"modified":"2025-06-13T14:24:37","modified_gmt":"2025-06-13T17:24:37","slug":"workshop-smx","status":"publish","type":"post","link":"https:\/\/pages.cnpem.br\/rau\/34th-rau\/workshop-smx\/","title":{"rendered":"Satellite SMX"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column width=&#8221;2\/3&#8243;][vc_text_separator title=&#8221;Description&#8221;][vc_column_text css=&#8221;&#8221;]<\/p>\n<p style=\"text-align: justify;\"><span data-contrast=\"auto\">The <a href=\"https:\/\/lnls.cnpem.br\/\" target=\"_blank\" rel=\"noopener\">Brazilian Synchrotron Light Laboratory (LNLS)<\/a> of the <a href=\"https:\/\/cnpem.br\/\" target=\"_blank\" rel=\"noopener\">Brazilian Center for Research in Energy and Materials (CNPEM)<\/a> will host the third <strong>Workshop SMX &#8211; MX at Sirius for Fragment Screening<\/strong>. This two-day workshop will be held on <strong>November 4 and 5, 2024<\/strong>, as one of the satellite events of the <strong>34th LNLS Annual Users Meeting<\/strong>.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:0,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-contrast=\"auto\">This workshop aims to bring together the LNLS community \u2013 external users, including students, researchers, and professionals \u2013 and experts working in the fields of structural biology, protein crystallography, and drug discovery, to disseminate the use of fragment screening and its implementation at the Manac\u00e1 beamline of the Sirius synchrotron.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:0,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span data-contrast=\"auto\">The first edition of SMX was held in November 2018, as one of the satellite workshops of the 28th RAU, focusing on the status and potentialities of the Manac\u00e1 beamline, which was still under construction at the time. In this edition, with the Manac\u00e1 beamline now in operation, the workshop aims to present the state-of-the-art in fragment screening using crystallography and its importance for drug discovery and the characterization of allosteric binding sites. National and international speakers will present the basic, practical aspects, and the status of fragment screening experiments in several open facilities.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:0,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\">We encourage participation in the workshop and RAU, but if you are only registering for this workshop and are interested in presenting your results, you can send the title and abstract to the following email:\u00a0<a href=\"mailto:andrey.nascimento@lnls.br\" data-linkindex=\"0\">andrey.nascimento@lnls.br<\/a>. The abstract must be sent in .pdf format following the same guidelines as RAU (2000 characters with spaces), <a href=\"https:\/\/pages.cnpem.br\/rau\/34th-rau\/registration\/\">https:\/\/pages.cnpem.br\/rau\/34th-rau\/registration\/<\/a>.<\/p>\n<p style=\"text-align: justify;\"><strong>Attention:<br \/>\n<\/strong><b>The deadline for abstract submission to the 3<sup>rd<\/sup>\u00a0SMX satellite workshop is <span style=\"color: #ff0000;\">23<sup>rd<\/sup> September<\/span>.*<\/b><\/p>\n<p style=\"text-align: justify;\">The selected abstracts may receive a travel grant. We will contact the authors after the deadline. If you have any question do not hesitate to contact us (above email).<\/p>\n<h6 style=\"text-align: justify;\"><strong>* <\/strong>This deadline is exclusive to the SMX Workshop. Submissions for the other workshops follow the schedule available under &#8220;important dates&#8221;.<\/h6>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_text_separator title=&#8221;Organization&#8221;][vc_empty_space height=&#8221;8px&#8221;][vc_cta h2=&#8221;&#8221; txt_align=&#8221;center&#8221; style=&#8221;outline&#8221; css=&#8221;&#8221;]<\/p>\n<p style=\"text-align: center;\"><strong>Chair<\/strong>: Andrey Fabricio Ziem Nascimento (LNLS\/CNPEM), Maria Cristina Nonato (FCFRP\/USP)<br \/>\n<strong>Co-chair<\/strong>: Daniela Barretto Barbosa Trivella (LNBio\/CNPEM)<br \/>\nEvandro Ares de Araujo (LNLS\/CNPEM)<br \/>\nManfred Weiss (Helmholtz-Zentrum Berlin)<br \/>\nUwe Mueller (Helmholtz-Zentrum Berlin)<\/p>\n<p>[\/vc_cta]<div class=\"uavc-list-icon uavc-list-icon-wrapper ult-adjust-bottom-margin   \"><ul class=\"uavc-list\"><li><div class=\"uavc-list-content\" id=\"list-icon-wrap-1013\">\n<div class=\"uavc-list-icon  \" data-animation=\"\" data-animation-delay=\"03\" style=\"margin-right:20px;\"><div class=\"ult-just-icon-wrapper  \"><div class=\"align-icon\" style=\"text-align:center;\">\n<div class=\"aio-icon circle \"  style=\"color:#ea5516;background:#094589;font-size:22px;display:inline-block;\">\n\t<i class=\"icomoon-the7-font-the7-map-02\"><\/i>\n<\/div><\/div><\/div>\n<\/div><span  data-ultimate-target='#list-icon-wrap-1013 .uavc-list-desc'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}'  class=\"uavc-list-desc ult-responsive\" style=\"\"><\/p>\n<div id=\"list-icon-wrap-1197\" class=\"uavc-list-content\"><span class=\"uavc-list-desc ult-responsive\" data-ultimate-target=\"#list-icon-wrap-1197 .uavc-list-desc\" data-responsive-json-new=\"{&quot;font-size&quot;:&quot;&quot;,&quot;line-height&quot;:&quot;&quot;}\"><strong>Event Location:<\/strong>\u00a0<span class=\"TextRun SCXW27537394 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW27537394 BCX0\" data-ccp-parastyle=\"Normal (Web)\">Auditorium \u2013 at Sirius entrance<\/span><\/span><span class=\"EOP SCXW27537394 BCX0\" data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:0,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/span><\/div>\n<p><\/span><\/div><\/li><\/ul><\/div>[\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;2\/3&#8243;][vc_text_separator title=&#8221;Program&#8221;][vc_tta_tabs][vc_tta_section title=&#8221;4 November&#8221; tab_id=&#8221;1716835338884-98818928-6916&#8243;][vc_cta h2=&#8221;&#8221; style=&#8221;outline&#8221; css=&#8221;&#8221;]<\/p>\n<table style=\"width: 100%; height: 462px;\" width=\"100%\">\n<tbody>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\" width=\"198\"><strong>Time<\/strong><\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\" width=\"427\"><strong>Satellite Workshop SMX<\/strong><\/td>\n<td style=\"width: 33.9467%; text-align: center; height: 22px;\"><strong>Speaker<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">08:00 &#8211; 08:30<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\" width=\"427\">Reception and Registration<\/td>\n<td style=\"width: 33.9467%; text-align: center; height: 22px;\"><strong>&#8211;<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">08:30 &#8211; 08:40<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\" width=\"427\">Welcome<\/td>\n<td style=\"width: 33.9467%; text-align: center; height: 22px;\">Committee<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">08:40 &#8211; 09:00<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\" width=\"427\">Soft and Biological Matter Division: An Overview<\/td>\n<td style=\"width: 33.9467%; text-align: center; height: 22px;\">Mateus Cardoso (LNLS\/CNPEM, Brazil)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">09:00 &#8211; 10:10<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\" width=\"427\"><strong>C1<\/strong> &#8211; Fragment-screening by crystallography: challenges and opportunities<\/td>\n<td style=\"width: 33.9467%; text-align: center; height: 22px;\">Manfred Weiss (HZB, Germany)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">10:10 &#8211; 10:40<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\" width=\"427\"><strong>Flash Talks (students)<\/strong><\/td>\n<td style=\"width: 33.9467%; text-align: center; height: 22px;\">Selected from abstracts<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">10:40 &#8211; 11:00<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\" width=\"427\"><strong>Coffee Break <\/strong><\/td>\n<td style=\"width: 33.9467%; text-align: center; height: 22px;\"><strong>&#8211;<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">11:00 &#8211; 11:20<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\"><strong>ST1 &#8211; <\/strong>Using a Fragment-based approach to target the endopeptidase RipA from Mycobacterium tuberculosis<\/td>\n<td style=\"width: 33.9467%; height: 22px; text-align: center;\"><span class=\"TextRun Highlight SCXW1807533 BCX0\" lang=\"PT-BR\" xml:lang=\"PT-BR\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW1807533 BCX0\">Catharina dos Santos<\/span> <span class=\"NormalTextRun SCXW1807533 BCX0\">Silva<\/span><span class=\"NormalTextRun SCXW1807533 BCX0\"> (USP, <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW1807533 BCX0\">Brazil<\/span><span class=\"NormalTextRun SCXW1807533 BCX0\">)<\/span><\/span><span class=\"EOP SCXW1807533 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">11:20 &#8211; 11:40<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\"><strong>ST2 &#8211; <\/strong>New HsDHODH Binding Sites Revealed by Crystallographic Fragment Screening<\/td>\n<td style=\"width: 33.9467%; height: 22px; text-align: center;\"><span class=\"TextRun Highlight SCXW118837211 BCX0\" lang=\"PT-BR\" xml:lang=\"PT-BR\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW118837211 BCX0\">Aline Dias da Purifica\u00e7\u00e3o<\/span><span class=\"NormalTextRun SCXW118837211 BCX0\"> (USP, <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW118837211 BCX0\">Brazil<\/span><span class=\"NormalTextRun SCXW118837211 BCX0\">)<\/span><\/span><span class=\"EOP SCXW118837211 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">11:40 &#8211; 12:15<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\"><strong>T1 &#8211;<\/strong> F<span class=\"TextRun Highlight SCXW206249515 BCX0\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW206249515 BCX0\">2X \u2013 The fragment screening facility of HZB<\/span><\/span><\/td>\n<td style=\"width: 33.9467%; height: 22px; text-align: center;\"><span class=\"TextRun Highlight SCXW45931064 BCX0\" lang=\"PT-BR\" xml:lang=\"PT-BR\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW45931064 BCX0\">Uwe Mueller (HZB, <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW45931064 BCX0\">Germany<\/span><span class=\"NormalTextRun SCXW45931064 BCX0\">)<\/span><\/span><span class=\"EOP SCXW45931064 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/td>\n<\/tr>\n<tr style=\"height: 44px;\">\n<td style=\"width: 19.26%; text-align: center; height: 44px;\">12:15 &#8211; 12:50<\/td>\n<td style=\"width: 45.5411%; text-align: center; height: 44px;\"><strong>T2 &#8211; <\/strong>The development of a fragment library at CRAFT<\/td>\n<td style=\"width: 33.9467%; text-align: center; height: 44px;\">Fl\u00e1vio Emery (USP, Brazil)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">12:50 &#8211; 14:00<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\"><strong>Lunch Break<\/strong><\/td>\n<td style=\"width: 33.9467%; height: 22px; text-align: center;\"><strong>&#8211;<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">14:00 &#8211; 14:30<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\">MANAC\u00c1 beamline visit<\/td>\n<td style=\"width: 33.9467%; height: 22px; text-align: center;\">Evandro Araujo (LNLS\/CNPEM, Brazil)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">14:30 &#8211; 15:05<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\"><strong>T3 &#8211;<\/strong> <span class=\"TextRun Highlight SCXW16039926 BCX0\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW16039926 BCX0\">A practical guide to crystallographic fragment screening<\/span><\/span><\/td>\n<td style=\"width: 33.9467%; height: 22px; text-align: center;\"><span class=\"TextRun Highlight SCXW197470060 BCX0\" lang=\"PT-BR\" xml:lang=\"PT-BR\" data-contrast=\"auto\"><span class=\"NormalTextRun SpellingErrorV2Themed SCXW197470060 BCX0\">Tatjana<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW197470060 BCX0\">Barthel<\/span><span class=\"NormalTextRun SCXW197470060 BCX0\"> (HZB, <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW197470060 BCX0\">Germany<\/span><span class=\"NormalTextRun SCXW197470060 BCX0\">)<\/span><\/span><span class=\"EOP SCXW197470060 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">15:05 &#8211; 15:40<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\"><strong>T4<\/strong> &#8211; Fragment screening at NSLS-II<\/td>\n<td style=\"width: 33.9467%; height: 22px; text-align: center;\">Dale Kreitler (NSLS-II, USA)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 19.26%; text-align: center;\">15:40 &#8211; 16:00<\/td>\n<td style=\"height: 22px; width: 45.5411%; text-align: center;\" width=\"427\"><strong>Coffee Break\u00a0<\/strong><\/td>\n<td style=\"width: 33.9467%; height: 22px; text-align: center;\"><strong>&#8211;\u00a0<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 44px;\">\n<td style=\"width: 19.26%; height: 44px; text-align: center;\">16:00 &#8211; 16:35<\/td>\n<td style=\"width: 45.5411%; height: 44px; text-align: center;\"><strong>T5 &#8211;<\/strong> The FragMAX facility for structure-based drug discovery at MAX IV Laboratory<\/td>\n<td style=\"width: 33.9467%; height: 44px; text-align: center;\">Tobias Krojer (MAX IV, Sweden)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"width: 19.26%; height: 22px; text-align: center;\">16:35 &#8211; 17:10<\/td>\n<td style=\"width: 45.5411%; height: 22px; text-align: center;\"><strong>T6 &#8211;<\/strong> Accelerating drug discovery with high-throughput crystallographic fragment screening\u00a0and structural enablement<\/td>\n<td style=\"width: 33.9467%; height: 22px; text-align: center;\">Daren Fearon (DLS, United Kingdom)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"width: 19.26%; height: 22px; text-align: center;\">17:10 &#8211; 17:30<\/td>\n<td style=\"width: 45.5411%; height: 22px; text-align: center;\"><strong>Discussion with the community<\/strong><\/td>\n<td style=\"width: 33.9467%; height: 22px; text-align: center;\"><strong>\u00a0&#8211;<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 19.26%; text-align: center;\">18:30<\/td>\n<td style=\"width: 45.5411%; text-align: center;\"><strong>Get together at a local brewery in Bar\u00e3o Geraldo<\/strong><\/td>\n<td style=\"width: 33.9467%; text-align: center;\"><strong>&#8211;<\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>[\/vc_cta][\/vc_tta_section][vc_tta_section title=&#8221;5 November&#8221; tab_id=&#8221;1716835338903-690858c1-0a3c&#8221;][vc_cta h2=&#8221;&#8221; style=&#8221;outline&#8221; css=&#8221;&#8221;]<\/p>\n<table style=\"width: 100%; height: 352px;\" width=\"100%\">\n<tbody>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\" width=\"198\"><strong>Time<\/strong><\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\" width=\"427\"><strong>Satellite Workshop SMX\u00a0<\/strong><\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\"><strong>Speaker<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">09:00 &#8211; 10:10<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\" width=\"427\"><strong>C2 &#8211;<\/strong> <span class=\"NormalTextRun SCXW183222162 BCX0\">Provisional title: <\/span><span class=\"NormalTextRun SCXW183222162 BCX0\">\u201c<\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW183222162 BCX0\">PanDDA<\/span><span class=\"NormalTextRun SCXW183222162 BCX0\"> \/ ligand ident. tool\u201d<\/span><\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\">Nicholas Pearce (Link\u00f6ping University, Sweden) &#8211; \ud83d\udcbb Remote presentation<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">10:10 &#8211; 10:30<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\" width=\"427\"><strong>ST3 &#8211; <\/strong><span class=\"TextRun SCXW244884388 BCX0\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW244884388 BCX0\">Exploring pyrazolopyrimidine as fragments: Developing an underexplored heterocycle library<\/span><\/span><\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\"><span class=\"TextRun SCXW118840136 BCX0\" lang=\"PT-BR\" xml:lang=\"PT-BR\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW118840136 BCX0\">Raul<\/span> <span class=\"NormalTextRun SCXW118840136 BCX0\">Marques<\/span> <span class=\"NormalTextRun SCXW118840136 BCX0\">Novais<\/span><span class=\"NormalTextRun SCXW118840136 BCX0\"> (USP, <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW118840136 BCX0\">Brazil<\/span><span class=\"NormalTextRun SCXW118840136 BCX0\">)<\/span><\/span><\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"width: 21.4458%; text-align: center; height: 22px;\">10:30 &#8211; 10:50<\/td>\n<td style=\"width: 41.9075%; text-align: center; height: 22px;\"><strong>Coffee Break\u00a0<\/strong><\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\">&#8211;<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">10:50 &#8211; 11:10<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\" width=\"427\"><strong>ST4 &#8211; <\/strong><span class=\"TextRun Highlight SCXW145787877 BCX0\" lang=\"EN-GB\" xml:lang=\"EN-GB\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW145787877 BCX0\">Elucidation of the Protein Structure of Enolase from Plasmodium falciparum<\/span><\/span><\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\"><span class=\"TextRun Highlight SCXW76651155 BCX0\" lang=\"PT-BR\" xml:lang=\"PT-BR\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW76651155 BCX0\">Gabriela Silva de Oliveira<\/span><span class=\"NormalTextRun SCXW76651155 BCX0\"> (USP, <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW76651155 BCX0\">Brazil<\/span><span class=\"NormalTextRun SCXW76651155 BCX0\">)<\/span><\/span><\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">11:10 &#8211; 11:45<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\" width=\"427\"><strong>T7 &#8211;<\/strong> An industrial perspective on fragment-based drug discovery using X-ray crystallography and cryo-EM<\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\">Gustavo Lima (Astex, Reino Unido)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">11:45 &#8211; 12:20<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\" width=\"427\"><strong>T8 &#8211;<\/strong>\u00a0Enabling FBDD projects using protein engineering: from fragments to clinic<\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\">Marko Hyv\u00f6nen (University of Cambridge\/USP)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">12:20 &#8211; 12:55<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\"><strong>T9 &#8211;<\/strong> Radical Innovation Strategy with Global Reach for the Pharmaceutical Sector in Brazil<\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\">Cristiano Guimar\u00e3es (Nintx, Brazil)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">12:55 &#8211; 14:00<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\" width=\"427\"><strong>Lunch Break<\/strong><\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\"><strong>\u00a0&#8211;<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">14:00 &#8211; 14:35<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\"><strong>T10 &#8211;<\/strong> Enabling viral targets through high-throughput crystallographic fragment screening at the AI-driven Structure-enabled Antiviral Platform (ASAP)<\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\">Andr\u00e9 Godoy (USP, Brazil)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">14:35 &#8211; 15:10<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\"><strong>T11 &#8211;<\/strong>\u00a0 Exploring Nature and Chemistry: Ach\u00e9\u2019s Approach to Drug Discovery<\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\">Hatylas Azevedo (Ach\u00e9, Brazil)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"width: 21.4458%; text-align: center; height: 22px;\">15:10 &#8211; 15:45<\/td>\n<td style=\"width: 41.9075%; text-align: center; height: 22px;\"><strong>T12 &#8211; <\/strong>Fragment-Based Campaign to Identify Novel Lead Starting points for critical targets of Mycobacterium tuberculosis<\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\">Marcio Dias (USP, Brazil)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">15:45 &#8211; 16:05<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\"><strong>Coffee Break\u00a0<\/strong><\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\"><strong>&#8211;<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">16:05 &#8211; 16:35<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\"><strong>T13 &#8211;<\/strong> Fragment Screening at CRAFT (Center for the research and advancement in fragments and molecular targets)<\/td>\n<td style=\"width: 35.3022%; text-align: center; height: 22px;\">Cristina Nonato (USP, Brazil)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">16:35 &#8211; 17:10<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\"><strong>T14 &#8211;<\/strong> Fragment screening-like approaches for fast discovery of natural product protein ligands and their binding sites<\/td>\n<td style=\"width: 35.3022%; height: 22px; text-align: center;\">Daniela Trivella (LNBio\/CNPEM, Brazil)<\/td>\n<\/tr>\n<tr style=\"height: 22px;\">\n<td style=\"height: 22px; width: 21.4458%; text-align: center;\">17:10 &#8211; 17:20<\/td>\n<td style=\"height: 22px; width: 41.9075%; text-align: center;\" width=\"427\"><strong>Closing Remarks<\/strong><\/td>\n<td style=\"width: 35.3022%; height: 22px; text-align: center;\">Committee<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>[\/vc_cta][\/vc_tta_section][\/vc_tta_tabs][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_text_separator title=&#8221;Topics&#8221;]<div class=\"standard-arrow bullet-top\"><ul>\n<li>Drug discovery using X ray crystallography<\/li>\n<li>Characterization of allosteric biding sites<\/li>\n<li>Crystallographic data processing for fragment screening<\/li>\n<li>Fragment screening and drug discovery at Sirius<\/li>\n<\/ul>\n<\/div>[vc_empty_space][vc_text_separator title=&#8221;Program&#8217;s Legends&#8221; css=&#8221;&#8221;]<div class=\"standard-arrow list-divider bullet-top\"><ul>\n<li><strong>C &#8211; <\/strong>\u00a0<strong>C<\/strong><strong>onference: <\/strong>1h talk + 10 min. questions<\/li>\n<li><strong>T &#8211; Talk:<\/strong> 30 min talk + 5 min. questions<\/li>\n<li><strong>ST &#8211; Student talk:<\/strong> 15 min + 3 min questions<\/li>\n<\/ul>\n<\/div>[vc_empty_space][vc_text_separator title=&#8221;Presentations&#8221; css=&#8221;&#8221;]<div class=\"standard-arrow list-divider bullet-top\"><ul>\n<li>The <strong>oral presentations <\/strong>(<strong>ST<\/strong>)\u00a0will last for <strong>15 minutes<\/strong>, followed by <strong>3 minutes for questions<\/strong> for each abstract (15+3min)<\/li>\n<\/ul>\n<\/div>[\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space height=&#8221;30px&#8221;][vc_text_separator title=&#8221;Invited Speakers&#8221; css=&#8221;&#8221;][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/3&#8243;]<div class=\"standard-arrow list-divider bullet-top\"><ul>\n<li><strong>Andr\u00e9 Godoy (USP, Brasil)<\/strong><\/li>\n<li><strong>Cristiano Guimar\u00e3es (Nintx, Brazil)<\/strong><\/li>\n<li><strong>Daniela Trivella (LNBio, CNPEM, Brasil)<\/strong><\/li>\n<li><strong>Daren Fearon (DLS, Reino Unido)<\/strong><\/li>\n<li><strong>Flavio da Silva Emery (USP, Brazil)<\/strong><\/li>\n<li><strong>Gustavo Lima (Astex, Reino Unido)<\/strong><\/li>\n<\/ul>\n<\/div>[\/vc_column][vc_column width=&#8221;1\/3&#8243;]<div class=\"standard-arrow list-divider bullet-top\"><ul>\n<li><strong>Hatylas Azevedo (Ach\u00e9, Brazil)<\/strong><\/li>\n<li><strong>Manfred Weiss (<\/strong><strong>Helmholtz-Zentrum Berlin, Alemanha)<\/strong><\/li>\n<li><strong>Marcio Dias (USP, Brasil)<\/strong><\/li>\n<li><strong>Maria Cristina Nonato (FCFRP, USP, Brasil)<\/strong><\/li>\n<li><strong>Marko Hyv\u00f6nen (University of Cambridge, United Kingdom \/ USP, Brazil)<\/strong><\/li>\n<\/ul>\n<\/div>[\/vc_column][vc_column width=&#8221;1\/3&#8243;]<div class=\"standard-arrow list-divider bullet-top\"><ul>\n<li><strong>Mateus Cardoso (LNLS, CNPEM, Brazil)<\/strong><\/li>\n<li><strong>Nicholas Pearce (Link\u00f6ping University, Su\u00e9cia)<\/strong><\/li>\n<li><strong>Tatjana Barthel (<\/strong><strong>Helmholtz-Zentrum Berlin, Alemanha)<\/strong><\/li>\n<li><strong>Tobias Krojer (MAX IV, Su\u00e9cia)<\/strong><\/li>\n<li><strong>Uwe Mueller (Helmholtz-Zentrum Berlin, Alemanha)<\/strong><\/li>\n<\/ul>\n<\/div>[\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space height=&#8221;30px&#8221;][vc_column_text css=&#8221;&#8221;]<\/p>\n<p style=\"text-align: center;\">This is a satellite workshop to the 34<sup>th<\/sup>\u00a0edition of the <a href=\"https:\/\/pages.cnpem.br\/rau\/34th-rau\/home\/\">Annual Users Meeting (RAU).<\/a><\/p>\n<p>[\/vc_column_text][vc_separator css=&#8221;&#8221;][vc_empty_space height=&#8221;15px&#8221;][vc_row_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;4911&#8243; img_size=&#8221;208&#215;88&#8243; onclick=&#8221;custom_link&#8221; img_link_target=&#8221;_blank&#8221; css=&#8221;&#8221; link=&#8221;http:\/\/www.iucr.org\/&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;][\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;][\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=&#8221;&#8221;]<\/p>\n<p style=\"text-align: justify;\"><span lang=\"en-GB\">This satellite workshop is supported by IUCr and agrees with gender balance policy.<\/span><\/p>\n<p><b><span lang=\"en-GB\">Statement on Gender Balance<br \/>\n<\/span><\/b><span lang=\"en-GB\">The Organizing Committee of 3<sup>rd<\/sup>\u00a0SMX fully supports and promotes gender equality in accordance with the IUCr policy:\u00a0<\/span><a href=\"https:\/\/www.iucr.org\/iucr\/principles-and-policies\/gender-balance\" target=\"_blank\" rel=\"noopener noreferrer\" data-auth=\"NotApplicable\" data-linkindex=\"3\"><span lang=\"en-GB\">IUCr statement on gender balance<\/span><\/a><\/p>\n<p style=\"text-align: justify;\"><span lang=\"en-GB\">We will ensure gender equality in our committees (including the Organizing Committee itself), among our lecturers and participants and pay special attention to the gender balance in evaluating bursary applications.<\/span><\/p>\n<p style=\"text-align: justify;\"><span lang=\"en-GB\">In accordance with IUCr policy, our gender statistics are collected and provided on our event webpage:<\/span><\/p>\n<p><span lang=\"en-GB\">Further information can be found on the web site of IUCR\u2019s Gender Equity and Diversity Committee GEDC (<\/span><a href=\"https:\/\/www.iucr.org\/iucr\/governance\/advisory-committees\/gedc\" target=\"_blank\" rel=\"noopener noreferrer\" data-auth=\"NotApplicable\" data-linkindex=\"4\"><span lang=\"en-GB\">https:\/\/www.iucr.org\/iucr\/governance\/advisory-committees\/gedc<\/span><\/a><span lang=\"en-GB\">). This page contains a code of conduct, a GEDC conference speaker statement and a toolkit for conference organizers: <\/span><a href=\"https:\/\/www.iucr.org\/__data\/assets\/pdf_file\/0008\/147923\/IUCr-GEDC-Code-of-Conduct.pdf\" target=\"_blank\" rel=\"noopener noreferrer\" data-auth=\"NotApplicable\" data-linkindex=\"5\"><span lang=\"en-GB\">IUCr Conference Code of Conduct<\/span><\/a><\/p>\n<p style=\"text-align: justify;\"><b><span lang=\"en-GB\">Scientific Freedom Policy Statement<br \/>\n<\/span><\/b>The Organizing Committee shall observe the basic policy of non-discrimination and affirms the right and freedom of scientists to associate in international scientific activity without regard to such factors as ethnic origin, religion, citizenship, language, political stance, gender, sex or age, in accordance with the Statutes of the International Council for Science. In our event no barriers will exist which would prevent the participation of bona fide scientists.<\/p>\n<p style=\"text-align: justify;\"><b><span lang=\"en-GB\">Diversity, Equality and Inclusion Statement<br \/>\n<\/span><\/b>We welcome all crystallographers and scientists working in related fields, regardless of their ethnic origin, race, citizenship, language, political views, gender, sex, sexual preferences, physical disabilities and age. We strive to create a culture of diversity, equality and inclusion.<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;2\/3&#8243;][vc_text_separator title=&#8221;Description&#8221;][vc_column_text css=&#8221;&#8221;] The Brazilian Synchrotron Light Laboratory (LNLS) of the Brazilian Center for Research in Energy and Materials (CNPEM) will host the third Workshop SMX &#8211; MX at Sirius for Fragment Screening. This two-day workshop will be held on November 4 and 5, 2024, as one of the satellite events of the 34th&hellip;<\/p>\n","protected":false},"author":3909,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[43],"tags":[],"class_list":["post-4972","post","type-post","status-publish","format-standard","hentry","category-34th-rau","category-43","description-off"],"_links":{"self":[{"href":"https:\/\/pages.cnpem.br\/rau\/wp-json\/wp\/v2\/posts\/4972","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pages.cnpem.br\/rau\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pages.cnpem.br\/rau\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pages.cnpem.br\/rau\/wp-json\/wp\/v2\/users\/3909"}],"replies":[{"embeddable":true,"href":"https:\/\/pages.cnpem.br\/rau\/wp-json\/wp\/v2\/comments?post=4972"}],"version-history":[{"count":0,"href":"https:\/\/pages.cnpem.br\/rau\/wp-json\/wp\/v2\/posts\/4972\/revisions"}],"wp:attachment":[{"href":"https:\/\/pages.cnpem.br\/rau\/wp-json\/wp\/v2\/media?parent=4972"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pages.cnpem.br\/rau\/wp-json\/wp\/v2\/categories?post=4972"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pages.cnpem.br\/rau\/wp-json\/wp\/v2\/tags?post=4972"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}